allergy is a disease caused by the immunological sensitization to food
proteins. Ingestion of triggering foods in sensitized patients leads to
gastro-intestinal, respiratory and skin symptoms, as well as life-threatening
anaphylaxis in severe cases. Patients experience significantly decreased
quality-of-life, since the only management option is avoidance of the offending
food with the constant risk of accidental ingestion. Thus there is a critical
need to develop treatment strategies targeting the immune system for
allergen-specific desensitization in food allergic patients.
ALLEVIATE project (https://innovationsfonden.dk/da/presse/foedevareallergi-skal-forebygges-og-behandles) aims to develop new treatment
strategies for food allergy using a novel vaccine approach.
connection to the ALLEVIATE project we are currently offering various projects
for students within:
development and screening of vaccine candidates for treatment of peanut allergy
of cow’s milk allergy in infants
studies for vaccines in food allergy
disease mechanisms in the sensitization and elicitation of food allergy
employ various methods for characterization of immune responses and vaccine
candidates, including animal experiments, ELISAs, PCR, histology, flow
cytometry, and biochemical characterization. Projects with a stronger focus on
more basic peptide chemistry or large-scale recombinant production of peptides
may be available through our collaborators.
preferably offer MSc projects, but special projects may also be available (e.g.
in combination with a following MSc project). A basic understand of biology,
biochemistry, immunology and/or microbiology is expected from candidates.
collaborators: DTU Food, DTU Chemistry, University of Leeds (UK), The Hospital
for Sick Children (CA), Medical University of Vienna (AT), and Arla Foods
information please contact Researcher Jeppe Madura Larsen (email@example.com) or
Senior Researcher Katrine Lindholm Bøgh (firstname.lastname@example.org).
I samarbejde medUniversity of Leeds (UK), The Hospital for Sick Children (CA), Medical University of Vienna (AT)