At DTU Nanotech
we conduct cross-disciplinary research where micro- and nanotechnology is
applied to a wide range of scientific disciplines as well as applications. The
Biomaterial Microsystems group is a highly ambitious group, pursuing research
on microfabrication of polymer and carbon structures and devices and their
application in drug delivery, bioelectrochemistry and micromechanical sensing.
nanotechnology is able to provide novel tools for diagnostics and health care.
Microneedles have been introduced as novel method for minimally invasive
transdermal drug delivery. However, so for only few studies on in situ sensing
with microneedle-based devices have been presented. At the same time,
electrochemistry offers a large range of methods for measurement of
biomolecules in physiological fluids.
In this MSc project we would like to explore microneedles for in situ
sensing of biomarkers in the skin. The objectives of the project include the
design and fabrication of the microneedle sensor at DTU Danchip and DTU
Nanotech. Assays for sensing of biomarkers will be established in collaboration
with a PhD student at DTU Nanotech. Finally, in vitro testing of the devices
will be performed.