Projekt

Can the interval between first and second heart sounds be used as an estimate for the QT-interval

Udbyder

Vejleder

Sted

København og omegn

Background:
Sudden cardiac death during sport events during sport events has been reported for both human and horses.

In humans it is known that some of these events are due to mutation or drugs that delay the repolarization phase of the cardiac action potential, which is reflected on the ECG as a an prolonged QT-interval.

This condition has accordingly been coined the Long QT Syndrome (LQTS), and is associated with ventricular fibrillation and sudden cardiac death.

Whether LQTS may also be relevant in equine medicine has yet to be established; In larger animals, such as the horse, the deflections on the ECG are not as well defined as in humans and they are often bi- or even triphasic. This makes it challenging to accurately measure the interval between the different peaks.


Our hypothesis is that the interval between heart sounds can be used to estimate the QT interval in larger animals, such as horses


Specific aims

• To build/modify ECG recording devices and electrodes to be used on large animals

• To develop a software program to analyse ECGs and heart sounds, including challenging ECGs like horse ECGs. This will make analysis faster and can be used of veterinarians that are not specialized in cardiology.

The results will be compared with measures performed manually
 

• The devices and program should preferably be able to determine the electrical axis of the animal/human.


Allowed no of students per report: 2


 

I samarbejde med

University of Copenhagen, Faculty of Health and Medical Sciences, Section for Anatomy, Biochemistry

Forudsætninger

The candidate for this project should have strong skills in engineering and software programming and be able to work independently.

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Kontakt

Virksomhed/organisation

DTU Sundhedsteknologi

Navn

Helge Bjarup Dissing Sørensen

Stilling

Gruppeleder, Lektor MSK, Ph.D.

Mail

hbds@dtu.dk

Vejleder-info

Bachelor i Medicin og Teknologi

Vejleder

Helge Bjarup Dissing Sørensen

Type

Bachelorprojekt, Kandidatspeciale

Kandidatuddannelsen i Medicin og Teknologi

Vejleder

Helge Bjarup Dissing Sørensen

Type

Bachelorprojekt, Kandidatspeciale

OM DTU

DTU er et teknisk eliteuniversitet med international rækkevidde og standard. Vores mission er at udvikle og nyttiggøre naturvidenskab og teknisk videnskab til gavn for samfundet. 10.000 studerende uddanner sig her til fremtiden, og 5.700 medarbejdere har hver dag fokus på uddannelse, forskning, myndighedsrådgivning og innovation, som bidrager til øget vækst og velfærd.

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Anker Engelunds Vej 1
Bygning 101A
2800 Kgs. Lyngby


45 25 25 25

dtu@dtu.dk

CVR-nr. 30 06 09 46

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