needles for drug delivery by injection are painful and problematic for people
with trypanophobia (fear of needles). Typically, this administration method
also requires health care professionals compared to e.g. oral drug delivery. In
the last few years, several approaches using microneedles for transdermal drug
delivery have been suggested. The miniaturization of the needles successfully
addresses the challenges mentioned above.
The aim of this
project is to fabricate a new type of biocompatible microneedles for
transdermal drug delivery. More specifically, the goal is to design
microneedles that are able to penetrate the skin and release the drug in a
controlled manner into skin tissue.
might partially be fabricated in the DTU Danchip cleanroom facilities. Penetration
of tissue and drug release will be characterized in the laboratories of DTU
Nanotech. First contacts for a possible collaboration with Leo Pharma have been
established and might be relevant depending on the selection of drug.