Projekt

Immune cell migration in Multiple Sclerosis

Udbyder

Vejleder

Sted

København og omegn

Understanding the migration of immune cells is paramount in a long range of pathological situations. Mapping of cell migration can be done longitudinally using non-invasive imaging of tagged cells.

The main focus of this project is to map the migration pattern of macrophages and T-cell subtypes in CNS inflammation in MS mice. This will be done with the use of Magnetic Resonance Imaging (MRI) using an exogenous contrast agent such as super-paramagnetic iodine oxide. SPIO.

Correlation of immune cell migration over time to the hallmarks of MS, demyelination and neural loss, as well as clinical disease, will make it possible to elucidate the impact of specific immune cell populations, with high detail and accuracy.

The experiment’s running at NMR center using the Bruker BioSpec 9.4 T MR small animal scanner. The candidate student will work with already optimized MR imaging protocols and will be involved in standardization and system calibration that are crucial in quantitative methods. Understanding the connection between the MR parameters and the biology is crucial, therefore the candidate will work in a highly interdisciplinary environment and will have the opportunity to collaborate with other researchers at the University of Copenhagen and BRIC.

Allowed no. of students: 1-2

I samarbejde med

Henrik El Ali, KU

Forudsætninger

Physics

Søg i opslag
Kontakt

Virksomhed/organisation

DTU Sundhedsteknologi

Navn

Thomas Sams

Stilling

Sektionsleder for Biomedical Engineering, Lektor, PhD

Mail

tsams@dtu.dk

Vejleder-info

Bachelor i Medicin og Teknologi

Vejleder

Thomas Sams

Type

Bachelorprojekt, Kandidatspeciale

Kandidatuddannelsen i Medicin og Teknologi

Vejleder

Thomas Sams

Type

Bachelorprojekt, Kandidatspeciale

OM DTU

DTU er et teknisk eliteuniversitet med international rækkevidde og standard. Vores mission er at udvikle og nyttiggøre naturvidenskab og teknisk videnskab til gavn for samfundet. 10.000 studerende uddanner sig her til fremtiden, og 5.700 medarbejdere har hver dag fokus på uddannelse, forskning, myndighedsrådgivning og innovation, som bidrager til øget vækst og velfærd.

Find os her

Anker Engelunds Vej 1
Bygning 101A
2800 Kgs. Lyngby


45 25 25 25

dtu@dtu.dk

CVR-nr. 30 06 09 46

Liste over EAN Numre

Job på DTU

Se alle jobs
 

loading..