Project

Development of vaccines for treatment of food allergy

Publisher

Supervisor

Location

Greater Copenhagen area

Food allergy is a disease caused by the immunological sensitization to food proteins. Ingestion of triggering foods in sensitized patients leads to gastro-intestinal, respiratory and skin symptoms, as well as life-threatening anaphylaxis in severe cases. Patients experience significantly decreased quality-of-life, since the only management option is avoidance of the offending food with the constant risk of accidental ingestion. Thus there is a critical need to develop treatment strategies targeting the immune system for allergen-specific desensitization in food allergic patients.

The ALLEVIATE project (https://innovationsfonden.dk/da/presse/foedevareallergi-skal-forebygges-og-behandles) aims to develop new treatment strategies for food allergy using a novel vaccine approach.

In connection to the ALLEVIATE project we are currently offering various projects for students within:

·        The development and screening of vaccine candidates for treatment of peanut allergy

·        Prevention of cow’s milk allergy in infants

·        Mechanism-of-action studies for vaccines in food allergy

·        Immunological disease mechanisms in the sensitization and elicitation of food allergy

Projects employ various methods for characterization of immune responses and vaccine candidates, including animal experiments, ELISAs, PCR, histology, flow cytometry, and biochemical characterization. Projects with a stronger focus on more basic peptide chemistry or large-scale recombinant production of peptides may be available through our collaborators.

We preferably offer MSc projects, but special projects may also be available (e.g. in combination with a following MSc project). A basic understand of biology, biochemistry, immunology and/or microbiology is expected from candidates.

ALLEVIATE collaborators: DTU Food, DTU Chemistry, University of Leeds (UK), The Hospital for Sick Children (CA), Medical University of Vienna (AT), and Arla Foods Ingredients.

For more information please contact Researcher Jeppe Madura Larsen (jeml@food.dtu.dk) or Senior Researcher Katrine Lindholm Bøgh (kalb@food.dtu.dk).

In collaboration with

University of Leeds (UK), The Hospital for Sick Children (CA), Medical University of Vienna (AT)

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Contact

Company / Organization

DTU Fødevareinstituttet

Name

Jeppe Madura Larsen

Position

Forsker

Mail

jeml@food.dtu.dk

Supervisor info

BSc in Biotechnology

Supervisor

Jeppe Madura Larsen

Type

Final project, BSc project, Course project, MSc thesis, Special course

BSc in Chemistry and Technology

Supervisor

Jeppe Madura Larsen

Type

Final project, BSc project, Course project, MSc thesis, Special course

BSc in Quantitative biology and disease modelling

Supervisor

Jeppe Madura Larsen

Type

Final project, BSc project, Course project, MSc thesis, Special course

BSc in Biomedical Engineering

Supervisor

Jeppe Madura Larsen

Type

Final project, BSc project, Course project, MSc thesis, Special course

Bachelor of Engineering, Food Safety and Quality (previously Food Analysis)

Supervisor

Jeppe Madura Larsen

Type

Final project, BSc project, Course project, MSc thesis, Special course

Kemi- og Bioteknologi

Supervisor

Jeppe Madura Larsen

Type

Final project, BSc project, Course project, MSc thesis, Special course

Food Analysis

Supervisor

Jeppe Madura Larsen

Type

Final project, BSc project, Course project, MSc thesis, Special course

MSc in Bioinformatics and Systems Biology

Supervisor

Jeppe Madura Larsen

Type

Final project, BSc project, Course project, MSc thesis, Special course

MSc in Biotechnology

Supervisor

Jeppe Madura Larsen

Type

Final project, BSc project, Course project, MSc thesis, Special course

MSc in Pharmaceutical Design and Engineering

Supervisor

Jeppe Madura Larsen

Type

Final project, BSc project, Course project, MSc thesis, Special course

MSc in Food Technology

Supervisor

Jeppe Madura Larsen

Type

Final project, BSc project, Course project, MSc thesis, Special course

MSc in Chemical and Biochemical Engineering

Supervisor

Jeppe Madura Larsen

Type

Final project, BSc project, Course project, MSc thesis, Special course

MSc in Biomedical Engineering

Supervisor

Jeppe Madura Larsen

Type

Final project, BSc project, Course project, MSc thesis, Special course

Technical University of Denmark

For almost two centuries DTU, Technical University of Denmark, has been dedicated to fulfilling the vision of H.C. Ørsted – the father of electromagnetism – who founded the university in 1829 to develop and create value using the natural sciences and the technical sciences to benefit society.


Today, DTU is ranked as one of the foremost technical universities in Europe, continues to set new records in the number of publications, and persistently increases and develops our partnerships with industry, and assignments accomplished by DTU’s public sector consultancy.

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