UV-lithography with FluorAcryl resist for generation of micro-droplet arrays




Greater Copenhagen area

Project description

Creating arrays of chemicals, proteins, and cells is of great interest in many biomedical applications. Previously, the pipetting technique has been widely used to create such arrays, but more sophisticated methods for rapid array creation is possible by exploiting lithographic techniques. The idea is to avoid the sequential process of the pipetting technique in favor of a parallel approach in order to save time and effort. This is obtained by making a spatial variance in both surface chemistry and structure, so that some superhydrophobic regions shed water, while other hydrophilic regions pin water droplets. The pinning regions get wetted, while the shedding regions stay dry, leaving behind the desired array pattern.


Characterization of the hydrophobic photo resist FluorAcryl 3298 : Make spin curves to find resist thickness as the function of spinner speed. Make a dose test to determine the full cross linking dose of this negative resist. Photolithography: Design a photomask with a pattern comprising an array of dots with different diameters and lattice constants and use the mask to expose the FluorAcryl resist. Preferably, define this pattern on a Si surface with a nano-grass pattern.  Characterization: Employ a contact angle goniometer with a high-speed camera to measure contact angles and roll-off angles of the structured surfaces. Test formation of micro-droplet arrays by dip-coating. Employ XPS (only master project) to characterize the surface chemistry of the exposed areas.

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Company / Organization

DTU Nanolab


Rafael J. Taboryski




Supervisor info

MSc in Physics and Nanotechnology


Rafael J. Taboryski


Nikolaj Kofoed Mandsberg


BSc project, MSc thesis

Technical University of Denmark

For almost two centuries DTU, Technical University of Denmark, has been dedicated to fulfilling the vision of H.C. Ørsted – the father of electromagnetism – who founded the university in 1829 to develop and create value using the natural sciences and the technical sciences to benefit society.

Today, DTU is ranked as one of the foremost technical universities in Europe, continues to set new records in the number of publications, and persistently increases and develops our partnerships with industry, and assignments accomplished by DTU’s public sector consultancy.

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