Project

Lactic acid bacteria are not optimized for fast growth – Metabolic control analysis of the purine biosynthesis

Publisher

Supervisor

Location

Greater Copenhagen area

All organisms can metabolize different intermediates in the nucleotide metabolism by the the salvage pathways. On the other hand, not all organisms can synthesize nucleotides de novo. Moreover, it has been shown that most – if not all – lactic acid bacteria have a partial purine requirement, meaning that they are not able to synthesize sufficient ATP and GTP when growing at their maximal growth rate. If shall be investigated whether to what extend a change of the expression of the purine biosynthetic genes affects the growth rate and the concentration of ATP and GTP.

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Contact

Company / Organization

DTU Bioengineering

Name

Jan Martinussen

Position

Lektor

Mail

jma@bio.dtu.dk

Supervisor info

BSc in Biotechnology

Supervisor

Jan Martinussen

Co-supervisors

Mogens Kilstrup

ECTS credits

5 - 30

Type

Final project, BSc project, Course project, MSc thesis, Special course

BSc in Human Life Science Engineering

Supervisor

Jan Martinussen

Co-supervisors

Mogens Kilstrup

ECTS credits

5 - 30

Type

Final project, BSc project, Course project, MSc thesis, Special course

Kemi- og Bioteknologi

Supervisor

Jan Martinussen

Co-supervisors

Mogens Kilstrup

ECTS credits

5 - 30

Type

Final project, BSc project, Course project, MSc thesis, Special course

MSc in Bioinformatics and Systems Biology

Supervisor

Jan Martinussen

Co-supervisors

Mogens Kilstrup

ECTS credits

5 - 30

Type

Final project, BSc project, Course project, MSc thesis, Special course

MSc in Biotechnology

Supervisor

Jan Martinussen

Co-supervisors

Mogens Kilstrup

ECTS credits

5 - 30

Type

Final project, BSc project, Course project, MSc thesis, Special course

Technical University of Denmark

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