Project

Development of a hypo-allergic cows milk formulation for infants

Publisher

Supervisor

Location

Greater Copenhagen area

Dietary formulation based on cow’s milk is a universal nutritional source for infants, and an important substitute for breastfeeding. However, cow’s milk allergy is one of the most common food allergies in children occurring after the ingestion and immunological sensitization to milk proteins. The disease afflicts 1-5 % of infants worldwide, and has significant impact on children’s nutritional state, particularly in children that cannot be breastfed, or live in areas with limited access to alternative foods.

In this project, we aim to develop a composition of cow’s milk infant formula that lowers the risk of milk allergy induction in infants. We employ a strategy to modify formula proteins to obtain a novel hypo-allergic composition. The project employs various methods for characterization of allergenicity, including animal experiments, ELISAs, PCR, histology, flow cytometry, and biochemical characterization.

We preferably offer MSc projects, but special projects may also be available (e.g. in combination with a following MSc project). A basic understand of biology, biochemistry, immunology and/or microbiology is expected from candidates.

This project is part of the larger ALLEVIATE project (https://innovationsfonden.dk/da/presse/foedevareallergi-skal-forebygges-og-behandles) funded by Innovation Fund Denmark.

ALLEVIATE collaborators: DTU Food, DTU Chemistry, University of Leeds (UK), The Hospital for Sick Children (CA), Medical University of Vienna (AT), and Arla Foods Ingredients.

For more information please contact Researcher Jeppe Madura Larsen (jeml@food.dtu.dk) or Senior Researcher Katrine Lindholm Bøgh (kalb@food.dtu.dk).


In collaboration with

University of Leeds (UK), The Hospital for Sick Children (CA), Medical University of Vienna (AT)

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Contact

Company / Organization

DTU Fødevareinstituttet

Name

Jeppe Madura Larsen

Position

Forsker

Mail

jeml@food.dtu.dk

Supervisor info

BSc in Biotechnology

Supervisor

Jeppe Madura Larsen

Type

Final project, BSc project, Course project, MSc thesis, Special course

BSc in Chemistry and Technology

Supervisor

Jeppe Madura Larsen

Type

Final project, BSc project, Course project, MSc thesis, Special course

BSc in Quantitative biology and disease modelling

Supervisor

Jeppe Madura Larsen

Type

Final project, BSc project, Course project, MSc thesis, Special course

BSc in Biomedical Engineering

Supervisor

Jeppe Madura Larsen

Type

Final project, BSc project, Course project, MSc thesis, Special course

MSc in Biotechnology

Supervisor

Jeppe Madura Larsen

Type

Final project, BSc project, Course project, MSc thesis, Special course

MSc in Pharmaceutical Design and Engineering

Supervisor

Jeppe Madura Larsen

Type

Final project, BSc project, Course project, MSc thesis, Special course

MSc in Food Technology

Supervisor

Jeppe Madura Larsen

Type

Final project, BSc project, Course project, MSc thesis, Special course

MSc in Chemical and Biochemical Engineering

Supervisor

Jeppe Madura Larsen

Type

Final project, BSc project, Course project, MSc thesis, Special course

MSc in Biomedical Engineering

Supervisor

Jeppe Madura Larsen

Type

Final project, BSc project, Course project, MSc thesis, Special course

Technical University of Denmark

For almost two centuries DTU, Technical University of Denmark, has been dedicated to fulfilling the vision of H.C. Ørsted – the father of electromagnetism – who founded the university in 1829 to develop and create value using the natural sciences and the technical sciences to benefit society.


Today, DTU is ranked as one of the foremost technical universities in Europe, continues to set new records in the number of publications, and persistently increases and develops our partnerships with industry, and assignments accomplished by DTU’s public sector consultancy.

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Denmark



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CVR-nr. 30 06 09 46

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