The aim of the project is to explore curing chemistries which can be utilized in a skin adhesive for an ostomy appliance. Moreover, toxicological aspects of the components should be considered as skin friendliness is a crucial parameter for adhesives applied on skin. The project work can involve synthesis, chemical characterization, and rheology.
Most curable adhesives on the market have some unfavorable properties. They might require high intensity ultraviolet light, high temperature, a long curing time, or undesired by-products are released. Furthermore, they might cause sensitization of the skin if they are not fully cured. For instance, moisture curing silicones either release a by-product e.g. acidic acid or have a long curing time.
Coloplast is the world leader within ostomy care and the project is related to this business area. The adhesive in an ostomy appliance is placed on the skin around a stoma.
The objective of the project is to synthesize polymers which can be utilized in a skin adhesive formulation for an ostomy appliance. The project can either focus on the effect of the polymer composition or the toxicological aspects of synthesized polymers. Thus the scope of the project will be agreed with the student. The project work will involve synthesis, chemical characterization, and rheology or cytoxicity tests.
The student should preferably have competencies within one or more of the following fields organic synthesis, polymer chemistry, chemical characterization, and rheology. Moreover, personal skills like self-dependence, studious, and approachable are preferred.
The project can either be carried out as a bachelor project or master project in collaboration with the Danish Polymer Centre (DPC) at Department of Chemical and Biochemical Engineering. Anders Egede Daugaard will be the supervisor from DPC and Charlotte Juel Fristrup, firstname.lastname@example.org will be responsible for the project from Coloplast. Most of the project work will be at DPC.
In collaboration withColoplast
Depends on the type of project and the amount of synthesis and characterization. The project can be directed towards a synthetic chemistry background and a more analytical profile.