Project

Finite element modeling of the biomechanics in the human heart

Publisher

Supervisor

Location

Greater Copenhagen area

Cardiovascular diseases (CVD) are the leading cause of death globally and were the cause of 1/3 of all deaths in the Western world in 2013.

It is estimated that 90% of CVD is preventable, thus, exams of the cardiovascular system are beneficial for evaluation, prevention and treatment.

Alterations of blood flow and dynamics are seen for almost all CVD of the heart. Hence, blood flow estimation is essential in the assessment of CVD, and is done both invasively and non-invasively depending on the heart condition.

Being able to observe cardiac blood flow velocity, volume flow rates, and pressure gradients in 3D in vivo will provide new insights into CVD. To evaluate emerging techniques for 3D in vivo imaging of the heart finite element models are often used as the reference.

This project covers design and validation of a finite element model of the biomechanics of human heart which covers both the fluid and solid mechanics.

The imaging data that is needed for the reconstruction of the cardiac geometry are obtained from the Østerbro study.

The project is expected to include segmentation of the human heart from CT scans, application of a blood flow model and a structural model of the cardiac muscle, and evaluation of model performance.

Requirements

This project comprises elements of fluid mechanics, structural mechanics and image processing. The student(s) should have experience with Matlab and Comsol Multiphysics.

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Contact

Company / Organization

DTU Sundhedsteknologi

Name

Marie Sand Traberg

Position

Gruppeleder, Lektor

Mail

msene@dtu.dk

Supervisor info

MSc in Biomedical Engineering

Supervisor

Marie Sand Traberg

Type

MSc thesis

Must be completed

31529 Tissue and Movement Biomechanics and/or 31545 Medical Imaging Systems can be an advantage

Technical University of Denmark

For almost two centuries DTU, Technical University of Denmark, has been dedicated to fulfilling the vision of H.C. Ørsted – the father of electromagnetism – who founded the university in 1829 to develop and create value using the natural sciences and the technical sciences to benefit society.


Today, DTU is ranked as one of the foremost technical universities in Europe, continues to set new records in the number of publications, and persistently increases and develops our partnerships with industry, and assignments accomplished by DTU’s public sector consultancy.

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2800 Kgs. Lyngby

Denmark



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CVR-nr. 30 06 09 46

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